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Infinite Loops

Apr 30, 2026

Saloni Dattani, author of the Scientific Discovery Substack and founding editor of Works in Progress magazine, joins Infinite Loops to discuss why medical innovation is often much slower than it needs to be.

We explore why so much research still begins in animal models, how poor data distorts our understanding of...


Apr 23, 2026

Why has America become so bad at building housing, infrastructure, and major projects?

Brian Potter, author of The Origins of Efficiency and writer of Construction Physics, explains why prefab housing keeps failing and why there are no easy fixes to America’s building problem. We discuss Katerra, California’s...


Apr 16, 2026

What can Aristotle, Plato, Prometheus, and the Greek city-states teach us about AI, innovation, and the future of human flourishing?

Alex Petkas joins the show to explore how old myths still matter in a world shaped by technology. We talk about Prometheus as the foundational myth of tech, Plato’s fear that writing...


Apr 9, 2026

Scientist and writer Sam Arbesman joins us for a wide-ranging conversation on AI, optimism, science, education, archives, science fiction, and why the history of computing still has so much to teach us.
 
We talk about why pessimism is often mistaken for sophistication, why AI may reward open-mindedness more...


Apr 2, 2026

Johnathan Bi returns to Infinite Loops for a conversation about founders, delusion, America, religion, mysticism, and the strange tension between truth and action.

We explore why some of the most effective builders may be the least introspective, why societies often run on useful fictions, how America encourages...